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Country of origin : China
1 products found

pp-119

Tablets, film coated

Dossier type
CTD
Dossier status
Under development
Country of origin
China
GMP approvals
China
Comments
"Indication: Immune-mediated inflammatory diseases, including hidradenitis suppurativa (HS) and other conditions driven by dysregulated innate immune signaling; focus on patients with moderate-to-severe disease inadequately controlled by standard therapies Clinical stage: Phase 1b clinical development (ongoing), with Phase 2 planned Modality: Small molecule Mechanism / Target: Selective RIPK2 (Receptor-interacting serine/threonine-protein kinase 2) inhibitor, blocking NOD1/NOD2 signaling pathways and downstream NF-κB–mediated inflammatory cytokine production Route / form: Oral Differentiation: Oral, targeted inhibition of RIPK2 offers a novel mechanism to modulate innate immune signaling upstream of multiple inflammatory pathways; potential for improved safety versus broad immunosuppressants and applicability across multiple inflammatory indications; positioned as a first-in-class approach in diseases like hidradenitis suppurativa
Manufacturer #29779

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