For over 25 years, the company has been specialty license holders and developers with their own staff working on innovative formulations and presentations. Own-label pharmaceutical, generic, and grocery markets expertise. Own-brand product made in an MHRA-approved facility. Reinvestment in new product development and approvals is ongoing. Export products to the Far East and Asia. Importing from outside the EU is a familiar concept.
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Vitamin B6
Vitamin B6 is water-soluble and in coenzyme forms, performs a wide variety of functions in
the body. It is known to be extremely versatile, with involvement in over 100 enzyme
reactions, mostly concerned with protein metabolism. Vitamin B6 is the generic name of six
compounds namely pyridoxine, alcohol, pyridoxal, an aldehyde, and pyridoxamine, which
contains an amino group and their respective 5’-phosphate esters and pyridoxamine 5’
phosphate are it’s coenzyme forms. It naturally occurs in diet, added to others, and even
available as a dietary supplement like fruits, vegetables, and grains that exist in glycosylated
forms. Vitamin B6 also plays a role in cognitive development as it enables the biosynthesis
of neurotransmitters and in maintaining normal levels of homocysteine. It is also involved in
gluconeogenesis and glycogenolysis, immune function, and hemoglobin formation. It is also
recommended in preventing and treating low levels of pyridoxine deficiency and the resulting
anemia. It is also used in the treatment of heart disease, Premenstrual syndrome, and
depression including other conditions.
Vitamin B6 is sold under the brand name Nestrex to name one. It is available a hundreds of
brands in many products and formulations treating so many conditions. It is one of the most
commonly occurring deficiency and thus governments and companies have ensured that
there are supplier, labelers and manufacturers around the world.
Dosing
The oral dose for adults when the body makes abnormal red blood cells that build up iron
called sideroblastic anemia, the initial dose is 200-600 mg and then decreased to 30-50 mg
per day after an adequate response. For treating vitamin B6 deficiency the dose for most
adults is 2.5-25 mg daily for three weeks then 1.5-2.5 mg per day. In the reduction of high
levels of homocysteine in the blood, the dose is 50-200 mg
In the treatment of conditions causing eye disease leading to vision loss in older adults the
dose is 50 mg of with 1000 mcg of vitamin B12 and 2500 mcg of folic acid for about 7 years
and For kidney stones, the prescribed dose is 25-500 mg daily. In the treatment of morning
sickness, the mother is given 10-25 mg, taken three or four times per day and in the
treatment of symptoms of premenstrual syndrome, the standard dose is 50-100 mg, used
daily along with 200 mg of magnesium.
The cost of Vitamin B6
In the USA, the consumers pay an average retail price of $3.20 for 30 tabs of 25mg. In India,
the cost of 100 tablets of the same strength is only USD1.
How does Vitamin B6 work?
Vitamin B6 (Pyridoxine) is needed for the proper function of sugars, fats, and proteins in the
body. It is also required for the proper growth and development of the brain, nerves, skin,
and many other parts of the body. The 4-methanol form, pyridoxine gets converted into
pyridoxal 5-phosphate, which is an important coenzyme for synthesis of amino acids,
neurotransmitters, sphingolipids, and aminolevulinic acid. Vitamin B6, in its biologically
active coenzyme form, is involved in a wide range of biochemical reactions, including the
metabolism of amino acids and glycogen, synthesis of nucleic acids, hemogloblin,
sphingomyelin, and sphingolipids. It is also responsible for the synthesis of the
neurotransmitters serotonin, dopamine, norepinephrine, and gamma-aminobutyric acid.
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